Precision Oncology

Precision Oncology | Dr Raman Narang – Medical Oncologist in Delhi

Precision oncology is a structured, evidence-based approach to cancer treatment that integrates tumor biology, molecular profiling, and patient-specific clinical factors.

Dr Raman Narang is a Consultant Medical Oncologist in Delhi with a focused interest in precision oncology, cancer genetics, and individualized systemic therapy. His clinical approach emphasizes rational treatment selection, biomarker-driven decisions, and careful treatment sequencing to optimize outcomes while preserving quality of life.

Precision oncology is not simply the use of newer drugs. It is the disciplined application of scientific insight to guide therapeutic strategy.


What Is Precision Oncology?

Precision oncology integrates molecular diagnostics, genomic insights, and clinical context to guide cancer treatment decisions.

Treatment planning is based on:

  • Tumor type and stage
  • Genomic alterations and biomarkers
  • Prior treatments
  • Organ function and performance status
  • Patient goals and life context

The objective is to match the right therapy to the right patient at the right time.

Role of Molecular Profiling & Cancer Genetics

Modern oncology increasingly relies on tumor genetic testing and biomarker analysis to guide therapy.

Dr Raman Narang provides structured guidance on:

  • Interpretation of molecular reports
  • Identification of actionable mutations
  • Understanding resistance mechanisms
  • Determining eligibility for targeted therapies or immunotherapy
  • Integrating genomic findings into overall treatment planning

This approach reduces empirical decision-making and strengthens therapeutic precision.

Immunotherapy & Targeted Therapy Selection

Immunotherapy and targeted therapies are selected based on defined biological markers rather than broad application.

Evaluation includes:

  • PD-L1 and other immunotherapy biomarkers
  • Tumor mutation burden where relevant
  • Driver mutations (EGFR, ALK, BRAF, etc., when applicable)
  • Prior lines of therapy
  • Potential benefit versus toxicity profile

Careful patient selection improves outcomes and minimizes unnecessary treatment exposure.

Structured Treatment Planning Approach

Precision oncology requires sequencing — not simply drug selection.

Clinical planning includes:

  • First-line therapy strategy
  • Anticipation of resistance patterns
  • Planning subsequent lines of treatment
  • Toxicity management
  • Integration with surgery or radiation when appropriate

Each case is evaluated individually rather than through protocol-driven uniformity.

Who Benefits from Precision Oncology?

Precision oncology is particularly valuable in:

  • Advanced or metastatic cancers
  • Rare tumor subtypes
  • Treatment-resistant disease
  • Patients seeking second opinion clarification
  • Younger patients requiring long-term survivorship planning

Second Opinion in Complex Cases

Many patients seek a structured second opinion to review:

  • Molecular test interpretation
  • Suitability of immunotherapy
  • Alternative treatment sequencing
  • Clinical trial eligibility
  • Risk-benefit balance of proposed therapy

Dr Raman Narang provides detailed, evidence-based second opinion consultations for patients in India and internationally.

Consultation Pathways

Patients may schedule:

  • In-person consultation in Delhi
  • Structured second opinion review
  • International case review

Cancer Treatment Across Age Groups

Geriatric Oncology (Older Adults)

Cancer treatment in older adults should be guided by functional assessment rather than chronological age.

Dr Raman Narang integrates:

  • Performance status and frailty assessment
  • Comorbidity burden
  • Organ function evaluation
  • Risk of treatment-related toxicity
  • Goals of care and quality-of-life priorities

Therapeutic decisions are individualized to balance disease control with safety, independence, and dignity.

Age alone should not determine intensity of therapy — structured assessment should.

Adolescent & Young Adult (AYA) Oncology

Young adults face unique medical and life-stage considerations during cancer treatment.

Planning includes attention to:

  • Fertility preservation
  • Long-term toxicity risks
  • Career and educational disruption
  • Survivorship planning
  • Psychosocial impact

Precision oncology plays a particularly important role in younger patients where long-term outcomes and treatment sequencing are critical.

As a Consultant Medical Oncologist in Delhi, Dr Raman Narang incorporates age-specific evaluation into precision treatment planning.

Frequently Asked Questions

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